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Post Info TOPIC: Anyone notice better dental health on rapamycin?


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Anyone notice better dental health on rapamycin?


 I've been on Rapa for three years and my last dental checkup looked great. I will have to go back and get copies of my records to verify improvements.  

    Taken together, our data demonstrate that a short-term treatment with rapamycin in aged mice is sufficient to target three clinically defining features of periodontal disease: periodontal bone loss, periodontal inflammation, and pathogenic changes to the oral microbiome. To the best of our knowledge, this is the first report of rejuvenation in the aged oral cavity. It will be important in future studies to determine whether these effects are mediated through local inhibition of mTORC1 in the gingiva and periodontal bone or through systemic effects on immune function or other tissues. Likewise, it will be of interest to understand whether additional features of oral health that are known to decline with age, such as salivary function, are improved by rapamycin treatment. Finally, these results suggest the intriguing likelihood that additional geroscience interventions, such clearance of senescent cells, may phenocopy the effects of rapamycin in this context. Such interventions could pave the way for the first effective treatments to reverse periodontal disease and improve oral health in the elderly.



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Anyone notice better dental health on rapamycin?




This is an exciting possibility of benefit. I will start self-experiment with rapamycin in a few weeks. I'm curious. Since you've used it for three years with an apparent lack of adverse effect, what is the dosage you are taking? Thanks

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Anyone notice better dental health on rapamycin?


Of course, I noticed that too. I think better dental health isn't only due to rapamycin but also to the fact that you've improved your diet. People who take a certain type of pill before or after a meal can easily normalize their diet. Before I started taking the pills, I ate twice a day. But now, my eating habit is at least five meals a day! This is good for the calcium level in our body. My dentist from https://thehealthysmile.net/dental-services/invisalign-bay-village-ohio/ explained this to me in a consultation. After such a detailed description, I realized I wanted to treat my and my children's teeth at this dental clinic.



-- Edited by joelynnpamplin on Thursday 30th of June 2022 08:24:29 AM

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